Diprolene AF Cream is indicated for relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients 13 years and older.
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The corticosteroids are a class of compounds comprising steroid hormones secreted by the adrenal cortex and their synthetic analogs. In pharmacologic doses, corticosteroids are used primarily for their antiinflammatory and/or immunosuppressive effects. Betamethasone dipropionate, a cortico steroid, has been shown to have topical (dermatologic) and systemic pharmacologic and metabolic effects characteristic of this class of drugs.
Diprolene comes in ointment, cream, lotion, and aerosol (spray) in various strengths for use on the skin. It is usually applied one to four times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Diprolene exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Do not apply it to other areas of your body or wrap or bandage the treated area unless directed to do so by your doctor.
The only local adverse reaction reported to be possibly or probably related to treatment with DIPROLENE AF Cream during adult, controlled clinical studies was stinging. It occurred in 1 patient, 0.4%, of the 242 patients or subjects involved in the studies.
Adverse reactions reported to be possibly or probably related to treatment with DIPROLENE AF Cream during a pediatric clinical study include signs of skin atrophy (telangiectasia, bruising, shininess). Skin atrophy occurred in 7 of 67 (10%) patients, involving all age groups from 3 months - 12 years of age.
The following local adverse reactions are reported infrequently when topical corticosteroids are used as recommended. These are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, miliaria.
Topically applied Diprolene AF can be absorbed in sufficient amounts to produce systemic effects. Seek emergency medical attention if an overdose is suspected.
Keep all appointments with your doctor.
Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.